Practice of Prevention of Mother-to-Child Transmission of HIV in the Gynecology-Obstetrics Department of the Ignace Deen National Hospital in Conakry

Introduction: Prevention of mother-to-child transmission, an important part of the overall management of HIV/AIDS infection, remains a challenge in the majority of resource-limited countries. Materials and Methods: This was a 6-month descriptive cross-sectional study from July 1 to December 31, 2023, carried out in the Gynecology-Obstetrics Department of the Ignace Deen National Hospital in Conakry, involving HIV-positive pregnant and parturient women who gave birth in the department and agreed to participate in the study during the study period. Results: The prevalence of HIV infection during pregnancy was (2.23%). The majority of patients were young with an average age of 28.30 ± 6 years, married (85.8%) and not in school (41.3%). The most numerous were pauciparous (40.2%) and those admitted for labor (51.1%) and PROM (23.9%). They were on triple therapy before admission (51.1%), with cesarean section (62%) as the most frequent method of delivery, and all had HIV type I. The viral load was undetectable in 68.7% of cases. Neonatal screening had involved 91.3% of cases and 93.5% of these newborns were put on Niverapine. The vertical transmission rate of HIV infection was 9.5%. Conclusion: Analysis of the results of this work shows that the prevalence of HIV infection during pregnancy is not negligible in our context. Early screening, early treatment of HIV-positive mothers and systematic viral load testing could further reduce the rate of vertical transmission of HIV infection.