Comparison of antimicrobial resistance and serotype patterns in <i>Streptococcus pneumoniae</i> from blood cultures and respiratory specimens in Canadian hospitals from the CANWARD study (2007–23)
S. pneumoniae from respiratory specimens demonstrated lower antimicrobial susceptibilities and higher MDR rates compared with isolates from blood cultures. Significant differences in the serotypes isolated from blood culture and respiratory specimens were observed. A greater proportion of isolates from blood cultures were serotypes covered by current pneumococcal vaccines.
Authors
- Alyssa Golden (ORCID: https://orcid.org/0000-0002-1788-1794)
- Heather J. Adam (ORCID: https://orcid.org/0000-0002-5646-6454)
- Melanie R. Baxter
- Irene Martín (ORCID: https://orcid.org/0000-0002-3941-5583)
- James A. Karlowsky (ORCID: https://orcid.org/0000-0002-1939-464X)
- George G. Zhanel (ORCID: https://orcid.org/0000-0002-3238-0082)
- Ross Davidson (ORCID: https://orcid.org/0000-0001-5361-0038)
Institutions
- Manitoba Health (CA)
- Public Health Agency of Canada (CA)
- Queen Elizabeth II Health Sciences Centre (CA)
- Health Sciences Centre (CA)
- Shared Health (CA)
- University of Manitoba (CA)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-08-28
- DOI
- https://doi.org/10.1093/jac/dkaf219
- Citations
- 2
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Pfizer
- University of Manitoba
- Merck Canada
- Sandoz Canada