Linezolid-related Optic Nerve Disorders: Insight From a Pharmacovigilance Analysis of the US FDA Adverse Event Reporting System
Among oxazolidinones, a signal for optic nerve disorders was detected exclusively for linezolid. Clinicians should ensure regular ophthalmologic monitoring during linezolid treatment, particularly in younger patients and those receiving high cumulative doses.
Authors
- Yuki Nakano (ORCID: https://orcid.org/0000-0002-0235-7615)
- Arisa Fukuyama
- Motoyasu Miyazaki (ORCID: https://orcid.org/0000-0002-4526-3045)
- Osamu Imakyure
- Hirotsugu Hasuwa
Institutions
- Daiichi University of Pharmacy (JP)
- Fukuoka University (JP)
- Fukuoka University Hospital (JP)
- Fukui-ken Saiseikai Hospital (JP)
- Saiseikai Fukuoka General Hospital (JP)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1093/ofid/ofaf520
- Citations
- 2
- Primary Topic
- Retinal and Optic Conditions
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- Servier