Comparison of the efficacy of single vs. double autologous platelet-rich plasma intrauterine infusion on endometrial receptivity in thin endometrium patients: a prospective randomized controlled trial

Compared to a single intrauterine infusion, double intrauterine PRP infusion may enhance the receptivity of a thin endometrium and improve clinical pregnancy outcomes. However, since the study population did not include patients with thin endometrium who also have a history of recurrent implantation failure or recurrent miscarriage, caution is advised when applying these findings to this specific group. Furthermore, these conclusions require validation through larger, randomized, multicenter trials.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2025-08-28
DOI
https://doi.org/10.3389/fendo.2025.1609556
Citations
2
Primary Topic
Sexual function and dysfunction studies
Type
article
Field-Weighted Citation Impact
2.94
Controls
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article

Comparison of the efficacy of single vs. double autologous platelet-rich plasma intrauterine infusion on endometrial receptivity in thin endometrium patients: a prospective randomized controlled trial

Derong Li, Yudi Luo, Lingling Zhu, Keng Feng et al.
2 citations
Frontiers in Endocrinology
Sexual function and dysfunction studies
2.94
article

Comparison of the efficacy of single vs. double autologous platelet-rich plasma intrauterine infusion on endometrial receptivity in thin endometrium patients: a prospective randomized controlled trial

Derong Li, Yudi Luo, Lingling Zhu, Keng Feng, Lei Li, Ling Wu, Luhai Ruan, Xiang Li
article en
2 citations

Abstract

Compared to a single intrauterine infusion, double intrauterine PRP infusion may enhance the receptivity of a thin endometrium and improve clinical pregnancy outcomes. However, since the study population did not include patients with thin endometrium who also have a history of recurrent implantation failure or recurrent miscarriage, caution is advised when applying these findings to this specific group. Furthermore, these conclusions require validation through larger, randomized, multicenter trials.

Frontiers in EndocrinologyVol. 16
Yulin Orthopedics Hospital of Chinese and Western Medicine (CN)
Openalex Percentile: Top 8%
Sexual function and dysfunction studies
2.94
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