How Does Cancer Escape the Body’s Defenses?

Did you know that your immune system is like a superhero team that can eliminate cancer cells before they are even detectable? Cancer starts when changes occur in the DNA of normal cells, causing them to turn into cancerous cells. Luckily, the body’s defense team—the immune system—is designed to detect these changes and fight the cancer cells. But why do people still get cancer? Scientists have developed a theory that explains this fight through three key phases: elimination, equilibrium, and escape. In the elimination phase, the immune system, like a vigilant hero, gets rid of most of the tumor cells. The cells that survive enter a sleep-like state called equilibrium. Eventually, these cells can wake up and use clever tactics to evade the immune system, moving into the escape phase. Understanding this process can help researchers develop new treatments to better combat cancer.

Authors

Publication Details

Journal
Frontiers for Young Minds
Published
2025-08-28
DOI
https://doi.org/10.3389/frym.2025.1256566
Primary Topic
Dietary Effects on Health
Type
article
Field-Weighted Citation Impact
0.00

Funders

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article

How Does Cancer Escape the Body’s Defenses?

Kevin Alicea-Torres, Lorraine M. Hernandez-Delgado, Gabriela Paz-Alvira, Adaliz J. Torres-Rosado
Frontiers for Young Minds
Dietary Effects on Health
article

How Does Cancer Escape the Body’s Defenses?

Kevin Alicea-Torres, Lorraine M. Hernandez-Delgado, Gabriela Paz-Alvira, Adaliz J. Torres-Rosado
article en

Abstract

Did you know that your immune system is like a superhero team that can eliminate cancer cells before they are even detectable? Cancer starts when changes occur in the DNA of normal cells, causing them to turn into cancerous cells. Luckily, the body’s defense team—the immune system—is designed to detect these changes and fight the cancer cells. But why do people still get cancer? Scientists have developed a theory that explains this fight through three key phases: elimination, equilibrium, and escape. In the elimination phase, the immune system, like a vigilant hero, gets rid of most of the tumor cells. The cells that survive enter a sleep-like state called equilibrium. Eventually, these cells can wake up and use clever tactics to evade the immune system, moving into the escape phase. Understanding this process can help researchers develop new treatments to better combat cancer.

Frontiers for Young MindsVol. 13
National Science Foundation, Ohio State University, National Institutes of Health, National Institute of General Medical Sciences
Openalex Percentile: Top 72%
Dietary Effects on Health
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How Does Cancer Escape the Body’s Defenses? — Kevin Alicea-Torres, Lorraine M. Hernandez-Delgado, et al. · Frontiers for Young Minds (2025) | TGRS Research Map | TGRS