Predictors of Discrepancies Between Cockcroft-Gault and Chronic Kidney Disease-EPI Creatinine-Cystatin in Hospitalized Patients
This study concluded that eCrCl may exceed eGFRcr-cys by >25 mL/min in patients presenting for hospital admission with one or more predictors: age <58 years, weight >105 kg, intensive care unit (ICU) admission, or diagnosis of paraplegia or quadriplegia. Current literature suggests improved accuracy of renal clearance estimations with eGFRcr-cys. Accordingly, practitioners should consider eGFRcr-cys when evaluating new admissions with these characteristics.
Authors
- S Poole
- Jordan L. Kelley
- Aric D. Schadler (ORCID: https://orcid.org/0000-0001-8814-5834)
- H.L. Matthews
- Ann Marie Stoll (ORCID: https://orcid.org/0000-0002-1861-7282)
- Charles Cornett
- A. Leonhard
- Audis Bethea (ORCID: https://orcid.org/0000-0002-0623-0478)
- Alexandra Sutphin
- Eden Brewington (ORCID: https://orcid.org/0000-0002-9532-2795)
Institutions
- University of Kentucky HealthCare (US)
- University of Kentucky (US)
- Cincinnati Health Department (US)
- University of Cincinnati (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1177/10600280251356492
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Center for Advancing Translational Sciences