Sleep Disorders and Gastric Cancer

Sleep disorders, including insomnia, obstructive sleep apnea, and poor sleep quality, have been linked to various health problems.Studies have extensively explored the association between sleep disorders and metabolic syndromes, such as cardiovascular diseases, diabetes, and obesity, with growing evidence suggesting their potential role in cancer development.This review focuses on the relationship between sleep disorders and gastric cancer, emphasizing epidemiologic evidence and potential mechanisms.We reviewed the current literature to examine the classification, prevalence, and pathologic mechanisms of sleep disorders, focusing on their role in the development of cancer.We assessed the association between sleep disorders and gastric cancer through epidemiologic studies, clinical data, and experimental research findings.Sleep disorders, such as insomnia and obstructive sleep apnea, are associated with increased inflammation, disrupted circadian rhythms, and impaired immune function, which may contribute to carcinogenesis.Epidemiologic studies show mixed results, with some reporting significant associations between short or excessively long sleep duration and the risk of gastric cancer.Additionally, narcolepsy and the evening chronotype may increase the risk of gastric cancer whereas the morning chronotype may have a protective effect.Sleep disorders may serve as significant risk factors for cancer, including gastric cancer.Short sleep duration and poor sleep quality are potential risk factors, whereas the morning chronotype may be protective.Future studies are warranted to establish the causal relationship between sleep disorders and cancer and to develop effective management and prevention strategies for at-risk populations.