Impact of acute alcohol intoxication and alcohol dependence on outcomes after subarachnoid hemorrhage
In patients with non-traumatic SAH, alcohol in the blood at the time of SAH is protective against 30-day mortality, and increased alcohol concentration adds increased protection. Paradoxically, alcohol use disorder leads to a worsening of clinical outcomes, including mortality. There appears to be a significant dose-dependent effect of severity of alcohol dependence on mortality.
Authors
- Eris Spirollari (ORCID: https://orcid.org/0000-0003-4468-9746)
- Uchenna Okafo
- Michael C. Schubert (ORCID: https://orcid.org/0000-0002-5975-374X)
- Ariel Sacknovitz (ORCID: https://orcid.org/0009-0008-6236-1190)
- Pankajavalli Ramakrishnan (ORCID: https://orcid.org/0000-0003-1576-2772)
- Ahamindra Jain
- Fawaz Al‐Mufti (ORCID: https://orcid.org/0000-0003-4461-7005)
- Elad Mashiach (ORCID: https://orcid.org/0000-0002-6135-6268)
- Stephan Mayer
- Isaac B. Thorman
- Rachid Kaddoura (ORCID: https://orcid.org/0009-0006-7614-2963)
- Jon Rosenberg (ORCID: https://orcid.org/0000-0003-1870-9854)
- Raghad Majid Al‐Saeed
- Chirag D. Gandhi
Institutions
- Westchester Medical Center (US)
- Johns Hopkins University (US)
- New York Medical College (US)
- Johns Hopkins Medicine (US)
- Mohammed Bin Rashid University of Medicine and Health Sciences (AE)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1007/s00701-025-06639-9
- Citations
- 2
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 2.94