A Multi-marker model based on serum IL-10 predicts response to conversion immunochemotherapy in gastric cancer patients: a retrospective cohort study
Dynamic monitoring of serum albumin, IL-10, and tumor-associated carbohydrate antigens can help assess treatment response and identify patients sensitive to conversion immunochemotherapy. For non-responsive patients, strategies such as the associations observed require validation in prospective interventional trials before specific interventions can be recommended.
Authors
- Xingzhou Wang
- Daming Cai
- Shichao Ai (ORCID: https://orcid.org/0000-0002-9691-0281)
- Xiaofei Shen (ORCID: https://orcid.org/0000-0002-5816-1814)
- Peng Song (ORCID: https://orcid.org/0000-0001-5165-0263)
- Hang Jiang (ORCID: https://orcid.org/0000-0002-8361-8206)
- Mengjie Liang
- Song Liu (ORCID: https://orcid.org/0000-0002-8719-0833)
- Meng Wang (ORCID: https://orcid.org/0000-0002-3457-5908)
- Feng Wang (ORCID: https://orcid.org/0000-0001-7462-3700)
- Xiaofeng Lu (ORCID: https://orcid.org/0009-0006-6164-8574)
- Wenxian Guan (ORCID: https://orcid.org/0000-0002-2171-6265)
- Liang Tao (ORCID: https://orcid.org/0000-0002-5092-9323)
- Xuefeng Xia (ORCID: https://orcid.org/0000-0002-6390-1709)
- Qiancheng Hu
- Feng Sun (ORCID: https://orcid.org/0000-0002-7052-6265)
Institutions
- Xuzhou Medical College (CN)
- Nanjing Drum Tower Hospital (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1186/s12876-025-04136-y
- Citations
- 2
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Government of Jiangsu Province
- Nanjing Drum Tower Hospital