Evaluation of Salvia yangii Extract as a Promising Protective Raw Material Applied Topically to the Skin
<i>Salvia yangii</i> is a popular garden plant known for its medicinal properties. The aim of this study was to evaluate the chemical composition and skin protective properties of <i>S. yangii</i> extracts, which have not previously been studied in this regard. Comparison of the water-ethanol extract obtained by ultrasound-assisted extraction (UAE) with a CO<sub>2</sub> extract showed that the former had higher content of polyphenolic compounds. Chromatographic analyses of UAE identified such phenolic compounds as rosmarinic acid, hesperidin, and caffeic acid. The biological properties of UAE were also tested in vitro on 15 microbial strains as well as on two lines of skin cells. In addition, a hydrogel and lotion based on the extract were tested for rheological and textural properties. This study showed that <i>S. yangii</i> extract can be a valuable natural cosmetic material owing to its antimicrobial, antioxidant, photoprotective, and anti-aging effects. The future use of <i>S. yangii</i> extracts in the cosmetic industry is promising due to its particular chemical profile and biological properties.
Authors
- Monika Michalak (ORCID: https://orcid.org/0000-0003-0471-3561)
- Dorota Kostrzewa (ORCID: https://orcid.org/0000-0002-5222-4394)
- Paulina Żarnowiec (ORCID: https://orcid.org/0000-0001-7670-3667)
- Małgorzata Stryjecka (ORCID: https://orcid.org/0000-0003-0230-8052)
- Martyna Zagórska-Dziok (ORCID: https://orcid.org/0000-0002-6947-1332)
- Natalia Dobros (ORCID: https://orcid.org/0000-0002-4281-3689)
- Aneta Ostróżka-Cieślik (ORCID: https://orcid.org/0000-0002-5179-1370)
- Anita Bocho–Janiszewska (ORCID: https://orcid.org/0000-0003-0529-1444)
- Katarzyna Paradowska
Institutions
- Jan Kochanowski University (PL)
- Medical University of Warsaw (PL)
- Kazimierz Pułaski University of Technology and Humanities in Radom (PL)
- Rejonowe Przedsiębiorstwo Wodociągów i Kanalizacji W Sosnowcu (Poland) (PL)
- University of Information Technology and Management in Rzeszow (PL)
- Łukasiewicz Research Network (PL)
- State School of Higher Education in Chełm (PL)
- New Chemical Syntheses Institute (PL)
- Institute of Occupational Medicine and Environmental Health (PL)
Publication Details
- Journal
- Molecules
- Published
- 2025-08-27
- DOI
- https://doi.org/10.3390/molecules30173505
- Citations
- 2
- Primary Topic
- Bee Products Chemical Analysis
- Type
- article
- Field-Weighted Citation Impact
- 3.34
Funders
- Uniwersytet Jana Kochanowskiego w Kielcach