Integration of single-cell and bulk RNA sequencing to identify unique tumor stem cells and construct novel prognostic markers for assessing ESCA prognosis and drug sensitivity
This study underscores the prognostic significance of the TSCMS model in ESCA, elucidates the immune landscape and treatment response, and identifies TSPO as a potential therapeutic target.
Authors
- Yu‐Chen Fan (ORCID: https://orcid.org/0000-0002-9126-679X)
- D. Qiao (ORCID: https://orcid.org/0000-0002-2754-7087)
- Beibei Sha
- Qian Lv (ORCID: https://orcid.org/0000-0002-0788-2451)
- Guiming Hu
- Longhao Wang (ORCID: https://orcid.org/0000-0002-4642-4701)
- Jia Shi (ORCID: https://orcid.org/0000-0002-4765-6512)
- Haibin Yu (ORCID: https://orcid.org/0000-0002-9563-9194)
Institutions
- Second Affiliated Hospital of Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-27
- DOI
- https://doi.org/10.3389/fonc.2025.1649877
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00