A retrospective analysis of neoadjuvant chemotherapy in pneumonectomy for locally advanced central non–small cell lung cancer
Neoadjuvant chemotherapy significantly improves prognosis in patients with locally advanced central NSCLC undergoing pneumonectomy. Multivariate analysis confirms its positive impact on survival. Patients who experience downstaging after neoadjuvant chemotherapy show notably better outcomes. For patients with stage cN2 disease, neoadjuvant chemotherapy is associated with improved survival.
Authors
- ZhiChao Dang (ORCID: https://orcid.org/0000-0002-4288-9843)
- Pu Jiang (ORCID: https://orcid.org/0000-0002-1942-5960)
- Zhifeng Li (ORCID: https://orcid.org/0000-0002-7647-0880)
- Kun Gao (ORCID: https://orcid.org/0000-0001-6651-8548)
- Jin Yang
- Yuchen Wang (ORCID: https://orcid.org/0009-0009-1031-4541)
- Xiaona Chen (ORCID: https://orcid.org/0000-0001-6241-811X)
- Ji‐Fang Yao
Institutions
- Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-08-27
- DOI
- https://doi.org/10.7717/peerj.20007
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00