Exploring the Interplay Among a Health-Promoting Lifestyle, Wellbeing, and Sociodemographic Characteristics in Italy: A Cross-Sectional Study

<b>Background:</b> A health-promoting lifestyle is a concept that involves sociodemographic factors interacting with health-promoting lifestyle behaviors (HPLBs), such as exercise and nutrition, to promote health and wellbeing. Given the persistent socioeconomic disparities all over Italy, health interventions and outcomes may be less effective. Accordingly, this cross-sectional study examines the relationship among sociodemographics, HPLBs, and wellbeing in Italy, aiming to inform updated health campaigns. <b>Methods:</b> A Google-Form survey of twelve sociodemographic items and two validated questionnaires on HPLBs (HPLP II, twenty-six items) and wellbeing (WHO-5) was conducted. Three hundred two participants, aged 18 to 70, were recruited in Italy via social media. Descriptive and inferential statistics were performed. Statistical significance was set at <i>p</i> < 0.05, considering effect sizes. <b>Results:</b> Women reported higher health responsibilities (<i>p</i> < 0.05) and lower BMIs than men (<i>p</i> < 0.001). An improved financial status was associated with the healthy cut-off points of the WHO-5, HPLP II total score, and spiritual growth and interpersonal relationship subscales (<i>p</i> < 0.001), the latter correlating also with university education (<i>p</i> < 0.05). Better nutrition was noted in older adults, those with chronic disease, and people from Northern Italy (<i>p</i> < 0.05). Residing with minors and adults related to health responsibility (<i>p</i> < 0.05). A significant correlation (<i>p</i> < 0.001) was found between following HPLBs and wellbeing and among all the HPLBs. <b>Conclusions:</b> This study underscores the interplay among sociodemographic factors, HPLBs, and wellbeing among Italian adults. The findings advocate for education-based, inclusive health promotion strategies tailored to specific macroregions, age classes, and sexes in Italy, intending to enhance overall health and wellbeing across the country.