BK polyomavirus genotype IV isolates from virus-specific T-cell therapy recipients
BK polyomavirus (BKPyV) can cause disease in transplant recipients. Virus-specific T-cell (VST) therapy is effective in decreasing virus levels in many individuals. BKPyV genetic variation can impact replication kinetics and immune responses. Here, we present the near full-length BKPyV genome sequences from two VST recipients in which genotype IV was isolated.
Authors
- Assem Ziady (ORCID: https://orcid.org/0000-0001-8959-7218)
- Benjamin L. Laskin (ORCID: https://orcid.org/0000-0002-9994-8509)
- Sonata Jodele (ORCID: https://orcid.org/0000-0002-1791-7718)
- Anthony Sabulski
- Stella M. Davies (ORCID: https://orcid.org/0000-0002-3137-6647)
- Michael Grimley (ORCID: https://orcid.org/0000-0003-2056-5167)
- Jeremy D. Rubinstein (ORCID: https://orcid.org/0000-0002-1934-2954)
- Alix E. Seif (ORCID: https://orcid.org/0000-0002-1799-2582)
- Jason T. Blackard (ORCID: https://orcid.org/0000-0003-2876-3811)
- Heidi L. Meeds (ORCID: https://orcid.org/0009-0001-3123-135X)
- Steven B. Kleiboeker
- Tiana A. Walder
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Children's Hospital of Philadelphia (US)
- Eurofins (United States) (US)
- Eurofins (France) (FR)
- University of Pennsylvania (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Microbiology Resource Announcements
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1128/mra.00625-25
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases