Living Donor Liver Transplantation for Symptomatic Liver Involvement in Infant With Hereditary Hemorrhagic Telangiectasia

This is the first report demonstrating the feasibility and effectiveness of LT in pediatric HHT patients with severe cardiac complications, including right-to-left shunting. The case highlights the natural history of HHT in childhood and provides guidance on optimal treatment strategies, particularly a decision to perform LT first while leaving right-to-left shunting and operative procedures to prevent perioperative complications.

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Publication Details

Journal
Hepatology Research
Published
2025-08-27
DOI
https://doi.org/10.1111/hepr.70020
Primary Topic
Vascular Anomalies and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Living Donor Liver Transplantation for Symptomatic Liver Involvement in Infant With Hereditary Hemorrhagic Telangiectasia

Takako Yoshioka, Masato Kojima, Chiduko Haga, Ryuji Komine et al.
Hepatology Research
Vascular Anomalies and Treatments
article

Living Donor Liver Transplantation for Symptomatic Liver Involvement in Infant With Hereditary Hemorrhagic Telangiectasia

Takako Yoshioka, Masato Kojima, Chiduko Haga, Ryuji Komine, Yusuke Yanagi, Mureo Kasahara, Akinari Fukuda, Seisuke Sakamoto, Hajime Uchida
article en

Abstract

This is the first report demonstrating the feasibility and effectiveness of LT in pediatric HHT patients with severe cardiac complications, including right-to-left shunting. The case highlights the natural history of HHT in childhood and provides guidance on optimal treatment strategies, particularly a decision to perform LT first while leaving right-to-left shunting and operative procedures to prevent perioperative complications.

Hepatology ResearchVol. 55(12)
National Center For Child Health and Development (JP)
Openalex Percentile: Top 70%
Vascular Anomalies and Treatments
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