CAKUT subtypes determine the rate of progression to kidney failure—an adult patient cohort study
CAKUT is genetically heterogeneous and the majority of cases remain genetically unresolved. Among patients on kidney replacement therapy, the rate of progression to KF is influenced by extrarenal presentation, bilateral kidney and urinary tract involvement and CAKUT subtype. Comprehensive interdisciplinary phenotypic characterization is essential and also contributes to a more accurate determination of kidney prognosis.
Authors
- Jan Halbritter (ORCID: https://orcid.org/0000-0002-1377-9880)
- Friederike Petzold (ORCID: https://orcid.org/0000-0003-3530-2888)
- Charlotte Hammett
- Sarah Stopp
- Jonathan de Fallois (ORCID: https://orcid.org/0000-0002-6448-1881)
- Eva Vanessa Schrezenmeier (ORCID: https://orcid.org/0000-0002-0016-7885)
- Klemens Budde (ORCID: https://orcid.org/0000-0002-7929-5942)
- Kai‐Uwe Eckardt (ORCID: https://orcid.org/0000-0003-3823-0920)
- Bernt Popp (ORCID: https://orcid.org/0000-0002-3679-1081)
- Annika Jens
- Guy Yealland
- Johannes Münch (ORCID: https://orcid.org/0000-0003-1779-1876)
- Carolin Brigl
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Hospital Leipzig (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University Medical Centre Mannheim (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Leipzig University (DE)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1093/ndt/gfaf172
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43