Association of plasma levels of protein-bound advanced glycation end-products and their soluble receptors with bone mineral status in young girls with the restrictive type of anorexia nervosa

To clarify the role of the AGEs/RAGE axis in anorexia nervosa-associated low bone mass, longitudinal studies assessing the dynamic changes of these markers during re-alimentation-induced weight restoration and bone health recovery are needed. In clinical practice, monitoring of the AGEs/sRAGE axis could offer a novel approach for assessing disease status and guiding personalized interventions to mitigate long-term health consequences in patients with AN.