The type 1 diabetes mellitus treatment

Type 1 diabetes mellitus is a non-communicable epidemic. The development of new treatment methods is aimed at eliminating the disease’s cause — autoimmune destruction of β-cells. Objective. To analyze the modern methods of treatment of type 1 diabetes mellitus. Materials and methods. Current publications containing information on the treatment of type 1 diabetes mellitus were analyzed during this study. Literature search was performed in eLibrary, PubMed, Cochrane Library and Cyberleninka databases. Results. The following modern methods of type 1 diabetes mellitus treatment have been considered: use of stem cells, immunotherapy, β-cell regeneration, transplantation of the pancreas or islets of Langerhans. Conclusion. Currently, the treatment of type 1 diabetes mellitus is not only aimed at compensation of insulin deficiency, but also at elimination of autoimmune β-cell destruction. Modern methods of type 1 diabetes mellitus treatment allow to change the approach to this disease. Stem cell therapy is the most promising method.

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Publication Details

Journal
Russian Journal of Preventive Medicine
Published
2025-08-27
DOI
https://doi.org/10.17116/profmed202528081131
Primary Topic
Diabetes Management and Research
Type
article
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article

The type 1 diabetes mellitus treatment

E. V. Penyaz', А. М. Morozov, V. A. Sitnova, A. Yu. Smyslova et al.
Russian Journal of Preventive Medicine
Diabetes Management and Research
article

The type 1 diabetes mellitus treatment

E. V. Penyaz', А. М. Morozov, V. A. Sitnova, A. Yu. Smyslova, Anastasia Tsvetkova
article en

Abstract

Type 1 diabetes mellitus is a non-communicable epidemic. The development of new treatment methods is aimed at eliminating the disease’s cause — autoimmune destruction of β-cells. Objective. To analyze the modern methods of treatment of type 1 diabetes mellitus. Materials and methods. Current publications containing information on the treatment of type 1 diabetes mellitus were analyzed during this study. Literature search was performed in eLibrary, PubMed, Cochrane Library and Cyberleninka databases. Results. The following modern methods of type 1 diabetes mellitus treatment have been considered: use of stem cells, immunotherapy, β-cell regeneration, transplantation of the pancreas or islets of Langerhans. Conclusion. Currently, the treatment of type 1 diabetes mellitus is not only aimed at compensation of insulin deficiency, but also at elimination of autoimmune β-cell destruction. Modern methods of type 1 diabetes mellitus treatment allow to change the approach to this disease. Stem cell therapy is the most promising method.

Russian Journal of Preventive MedicineVol. 28(8)
Tver State Medical University (RU), City Clinical Hospital (RU)
Openalex Percentile: Top 69%
Diabetes Management and Research
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The type 1 diabetes mellitus treatment — E. V. Penyaz', А. М. Morozov, et al. · Russian Journal of Preventive Medicine (2025) | TGRS Research Map | TGRS