Desafios terapêuticos na dermatite urêmica e cicatrização em cão com doença renal crônica

Chronic Kidney Disease (CKD) is an irreversible condition commonly seen in older dogs, characterized by the progressive loss of kidney function. This paper reports the case of a mixed-breed dog, approximately nine years old, diagnosed with CKD and presenting with chronic, non-healing paw wounds. Treatment included fluid therapy, daily dressings with chlorhexidine and activated charcoal, as well as the administration of erythropoietin, Geriox®, and aluminum hydroxide. Despite these measures, the skin lesions showed unfavorable progression, possibly associated with poor tissue oxygenation, metabolic acidosis, and immunosuppression—common complications in CKD. Wound healing improved after discontinuation of the dressings. However, the animal died several months later due to complications of the disease. This case highlights the clinical challenges of wound management in patients with CKD and underscores the importance of an individualized therapeutic approach that takes into account the disease’s metabolic and systemic effects. Early intervention and continuous monitoring are essential to improving the quality of life of these patients, although the prognosis remains reserved at advanced stages.