Idiopathic hypereosinophilic syndrome: Potential pathologic somatic gene variants identified by exome sequencing
Several somatic mutations were identified in our cohort of patients with idiopathic HES. Increasing the number of patients through collaborative efforts and pursuing functional testing of these variants will help elucidate the importance of these genes in idiopathic HES.
Authors
- Thanai Pongdee (ORCID: https://orcid.org/0000-0002-4725-242X)
- Mrunal Dehankar (ORCID: https://orcid.org/0000-0002-5953-9495)
- Mrinal M. Patnaik (ORCID: https://orcid.org/0000-0001-6998-662X)
- Alejandro Tiana Ferrer
- Saurabh Baheti (ORCID: https://orcid.org/0000-0002-3564-7627)
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1016/j.jacig.2025.100563
- Primary Topic
- Eosinophilic Disorders and Syndromes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Center for Individualized Medicine, Mayo Clinic