Outcomes following exploratory surgery without subsequent resection in perihilar cholangiocarcinoma: A nationwide analysis
Among patients with non-metastatic pCCA receiving systemic therapy, survival outcomes are comparable between those who undergo surgical exploration and those who do not. Despite a possible impact on quality of life, these findings suggest that surgical exploration does not hinder access to systemic therapy or negatively affect survival.
Authors
- Robert C. Verdonk (ORCID: https://orcid.org/0000-0001-5591-0499)
- Jelmer E. Oor (ORCID: https://orcid.org/0000-0001-5724-6587)
- Frank G. Schaap (ORCID: https://orcid.org/0000-0002-1597-572X)
- Bas Groot Koerkamp (ORCID: https://orcid.org/0000-0003-1917-6973)
- Judith de Vos‐Geelen (ORCID: https://orcid.org/0000-0003-2578-1766)
- Frederik J.H. Hoogwater (ORCID: https://orcid.org/0000-0002-3320-7185)
- Steven W.M. Olde Damink (ORCID: https://orcid.org/0000-0002-5202-9345)
- Joanne Verheij (ORCID: https://orcid.org/0000-0003-1283-630X)
- Joris I. Erdmann (ORCID: https://orcid.org/0000-0001-8233-1505)
- Razvan L. Miclea (ORCID: https://orcid.org/0000-0002-9136-3020)
- Iryna Samarska (ORCID: https://orcid.org/0000-0003-4092-0672)
- J. Luyten (ORCID: https://orcid.org/0000-0003-2350-1521)
- Maxime Dewulf (ORCID: https://orcid.org/0000-0002-1945-5481)
- Jan Bednarsch (ORCID: https://orcid.org/0000-0001-8143-6452)
- Marjolein Y.V. Homs (ORCID: https://orcid.org/0000-0001-9828-2541)
- Lydia G. van der Geest (ORCID: https://orcid.org/0000-0003-1637-5520)
- Jeroen Hagendoorn (ORCID: https://orcid.org/0000-0001-8737-3923)
- Ulf P. Neumann (ORCID: https://orcid.org/0000-0002-3831-8917)
- Willem F Brandts
Institutions
- University Medical Center Groningen (NL)
- Heidelberg University (DE)
- Maastricht University Medical Centre (NL)
- University Hospital Heidelberg (DE)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- St. Antonius Ziekenhuis (NL)
- Essen University Hospital (DE)
- Netherlands Comprehensive Cancer Organisation (NL)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam University of Applied Sciences (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-08-27
- DOI
- https://doi.org/10.1016/j.ejso.2025.110419
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- AstraZeneca
- Servier