Fever, Malaise, and Weight Loss in a Woman With Aortic Valve Replacement

A patient with a bioprosthetic aortic valve implanted 6 years prior to presentation had fevers, malaise, and weight loss. Coxiella burnetii titers, erythrocyte sedimentation rate, and levels of C-reactive protein and rheumatoid factor were elevated; transesophageal echocardiography showed a thickened aortic root. What is the diagnosis and what would you do next?

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Publication Details

Journal
JAMA
Published
2025-08-27
DOI
https://doi.org/10.1001/jama.2025.13036
Primary Topic
Infective Endocarditis Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Fever, Malaise, and Weight Loss in a Woman With Aortic Valve Replacement

Annina Studer Bruengger, Cinzia Ullrich, Lars C Huber
JAMA
Infective Endocarditis Diagnosis and Management
article

Fever, Malaise, and Weight Loss in a Woman With Aortic Valve Replacement

Annina Studer Bruengger, Cinzia Ullrich, Lars C Huber
article en

Abstract

A patient with a bioprosthetic aortic valve implanted 6 years prior to presentation had fevers, malaise, and weight loss. Coxiella burnetii titers, erythrocyte sedimentation rate, and levels of C-reactive protein and rheumatoid factor were elevated; transesophageal echocardiography showed a thickened aortic root. What is the diagnosis and what would you do next?

JAMAVol. 334(12)
Stadtspital Waid (CH)
Openalex Percentile: Top 69%
Infective Endocarditis Diagnosis and Management
DOISourceOpenAlex
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Fever, Malaise, and Weight Loss in a Woman With Aortic Valve Replacement — Annina Studer Bruengger, Cinzia Ullrich, et al. · JAMA (2025) | TGRS Research Map | TGRS