MediGuard: Protecting Sensitive Healthcare Data with Privacy-Preserving Language Models

The integration of large language models (LLMs) into digital healthcare has the potential to significantly improve access to accurate and timely medical advice, especially in underserved areas. However, serious privacy concerns hinder the widespread adoption of LLM-based medical consultation systems, as they often require users to disclose private health information, risking unauthorized exposure and non-compliance with regulations. To address these issues, we introduce MediGuard, a new privacy-preserving LLM framework that dynamically protects sensitive healthcare data throughout the consultation process. MediGuard employs adaptive information obfuscation, combined with secure access protocols and robust auditing mechanisms, to process only non-sensitive information while preserving the necessary semantic integrity for precise medical inference and decision-making. Extensive testing across multiple medical question-answering datasets demonstrates that MediGuard consistently outperforms existing methods in both privacy protection and clinical accuracy, even under stringent privacy constraints. Our findings suggest that MediGuard provides safe, trustworthy, and clinically reliable medical consultations, setting a new standard for privacy-aware healthcare AI.

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Publication Details

Journal
IEEE Journal of Biomedical and Health Informatics
Published
2025-01-01
DOI
https://doi.org/10.1109/jbhi.2025.3602983
Citations
1
Primary Topic
Privacy-Preserving Technologies in Data
Type
article
Field-Weighted Citation Impact
2.48
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article

MediGuard: Protecting Sensitive Healthcare Data with Privacy-Preserving Language Models

Daehan Kwak, Naqqash Dilshad, Farman Ali, Babar Shah et al.
1 citations
IEEE Journal of Biomedical and Health Informatics
Privacy-Preserving Technologies in Data
2.48
article

MediGuard: Protecting Sensitive Healthcare Data with Privacy-Preserving Language Models

Daehan Kwak, Naqqash Dilshad, Farman Ali, Babar Shah, Haseeb Javed
article en
1 citations

Abstract

The integration of large language models (LLMs) into digital healthcare has the potential to significantly improve access to accurate and timely medical advice, especially in underserved areas. However, serious privacy concerns hinder the widespread adoption of LLM-based medical consultation systems, as they often require users to disclose private health information, risking unauthorized exposure and non-compliance with regulations. To address these issues, we introduce MediGuard, a new privacy-preserving LLM framework that dynamically protects sensitive healthcare data throughout the consultation process. MediGuard employs adaptive information obfuscation, combined with secure access protocols and robust auditing mechanisms, to process only non-sensitive information while preserving the necessary semantic integrity for precise medical inference and decision-making. Extensive testing across multiple medical question-answering datasets demonstrates that MediGuard consistently outperforms existing methods in both privacy protection and clinical accuracy, even under stringent privacy constraints. Our findings suggest that MediGuard provides safe, trustworthy, and clinically reliable medical consultations, setting a new standard for privacy-aware healthcare AI.

IEEE Journal of Biomedical and Health InformaticsVol. PP
Sejong University (KR), Kean University (US), Sungkyunkwan University (KR), Zayed University (AE)
Openalex Percentile: Top 9%
Privacy-Preserving Technologies in Data
2.48
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MediGuard: Protecting Sensitive Healthcare Data with Privacy-Preserving Language Models — Daehan Kwak, Naqqash Dilshad, et al. · IEEE Journal of Biomedical and Health Informatics (2025) | TGRS Research Map | TGRS