Nasal Mucosal Manifestation of Behçet's Disease: A Case Report

Behçet's disease (BD) is a multisystem inflammatory condition that rarely affects the nasal mucosa. We report the case of a 25-year-old man presenting with prolonged fever, bilateral rhinalgia, and nasal obstruction, who was subsequently diagnosed with nasal ulcers associated with BD. These ulcers resolved along with the systemic symptoms following treatment with colchicine, apremilast, and prednisolone. Although there is no specific treatment strategy for nasal mucosal lesions in BD, standard systemic therapies may be effective. This case highlights nasal mucosal involvement as a rare but important manifestation of BD, emphasizing the importance of thorough evaluation and consideration of nasal symptoms for the diagnosis and treatment.

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Publication Details

Journal
Internal Medicine
Published
2025-01-01
DOI
https://doi.org/10.2169/internalmedicine.6014-25
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
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article

Nasal Mucosal Manifestation of Behçet's Disease: A Case Report

Yu Katayama, Hideharu Hagiya, Aki Sato, Yuki Otsuka et al.
Internal Medicine
Ocular Diseases and Behçet’s Syndrome
article

Nasal Mucosal Manifestation of Behçet's Disease: A Case Report

Yu Katayama, Hideharu Hagiya, Aki Sato, Yuki Otsuka, Yoshiaki Soejima, Fumio Otsuka, Yohei Masuda, Kenta Nakamoto, Hiroshi Akiyama
article en

Abstract

Behçet's disease (BD) is a multisystem inflammatory condition that rarely affects the nasal mucosa. We report the case of a 25-year-old man presenting with prolonged fever, bilateral rhinalgia, and nasal obstruction, who was subsequently diagnosed with nasal ulcers associated with BD. These ulcers resolved along with the systemic symptoms following treatment with colchicine, apremilast, and prednisolone. Although there is no specific treatment strategy for nasal mucosal lesions in BD, standard systemic therapies may be effective. This case highlights nasal mucosal involvement as a rare but important manifestation of BD, emphasizing the importance of thorough evaluation and consideration of nasal symptoms for the diagnosis and treatment.

Internal Medicine
Okayama University (JP), Okayama University Hospital (JP)
Zero hunger
Openalex Percentile: Top 66%
Ocular Diseases and Behçet’s Syndrome
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Nasal Mucosal Manifestation of Behçet's Disease: A Case Report — Yu Katayama, Hideharu Hagiya, et al. · Internal Medicine (2025) | TGRS Research Map | TGRS