Malignant peripheral nerve sheath tumor in the vagus nerve causing upper gastrointestinal signs in a dog

Peripheral nerve sheath tumors (PNSTs) originating from the vagus nerve are rare in dogs. This paper reports a canine case of malignant PNST originating from the vagus nerve, specifically the vagus-sympathetic trunk, which induced notable gagging and chronic vomiting. The clinical signs improved after surgery despite incomplete resection, and the dog achieved an overall survival of at least 514 days. These observations suggest that surgical intervention may be beneficial in dogs with malignant PNSTs originating from the vagus nerve.

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Publication Details

Journal
Journal of Veterinary Medical Science
Published
2025-01-01
DOI
https://doi.org/10.1292/jvms.25-0152
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

Malignant peripheral nerve sheath tumor in the vagus nerve causing upper gastrointestinal signs in a dog

James Chambers, Taisuke Nakagawa, Yosuke Takahashi, Fumitaka Shitamori et al.
1 links
Journal of Veterinary Medical Science
Neurofibromatosis and Schwannoma Cases
article

Malignant peripheral nerve sheath tumor in the vagus nerve causing upper gastrointestinal signs in a dog

James Chambers, Taisuke Nakagawa, Yosuke Takahashi, Fumitaka Shitamori, Hirotaka Tomiyasu, Kie Yamamoto, Naohiro TAKAHASHI, Megumi SAKAMOTO, Kazuyuki Uchida
article en

Abstract

Peripheral nerve sheath tumors (PNSTs) originating from the vagus nerve are rare in dogs. This paper reports a canine case of malignant PNST originating from the vagus nerve, specifically the vagus-sympathetic trunk, which induced notable gagging and chronic vomiting. The clinical signs improved after surgery despite incomplete resection, and the dog achieved an overall survival of at least 514 days. These observations suggest that surgical intervention may be beneficial in dogs with malignant PNSTs originating from the vagus nerve.

Journal of Veterinary Medical ScienceVol. 87(10)
Veterinary Medical Center (JP), The University of Tokyo (JP)
Openalex Percentile: Top 67%
Neurofibromatosis and Schwannoma Cases
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Malignant peripheral nerve sheath tumor in the vagus nerve causing upper gastrointestinal signs in a dog — James Chambers, Taisuke Nakagawa, et al. · Journal of Veterinary Medical Science (2025) | TGRS Research Map | TGRS