Nanoparticles Crossing the Blood–Brain Barrier: A Hope for Central Nervous System Disorders

It has been estimated that about 1.5 million deaths occur due to central nervous system disorders. The problem is overcome by modern pharmaceutical technology by manufacturing nanoparticles. These are small particles that have an advantage over other drugs because they have the ability to pass through the blood–brain barrier, which is a structure in the brain that maintains the transport of substances and drugs between blood and brain. Nanoparticles are of different types. They may be polymeric, liposomal, or solid lipid nanoparticles. The main aim of nanoparticles is the target-specific delivery of drugs.