Adenomyosis in Focus: Age-Related Trends and the Lack of Cardiovascular Risk Factor Correlation

Objective: Adenomyosis is a common benign gynecological pathology that is frequently associated with endometriosis. Although numerous studies have investigated cardiovascular risk factors in endometriosis, research on these risks in patients with adenomyosis remains scarce. This study aimed to evaluate cardiovascular risk factors in patients diagnosed with adenomyosis. Method: A total of 135 patients (65-study group, 70-control group) were included in the study. Age, known chronic comorbidities, smoking status, blood pressure, body mass index (BMI), and waist-to-hip ratio (WHR) were recorded preoperatively. Blood samples were obtained from patients who received pathology results within the first month after surgery. To evaluate cardiovascular risk factors, tests for total cholesterol, HDL, LDL, triglycerides, and CRP levels were performed. Results: The presence of chronic diseases and smoking status were compared between groups, and no significant differences were found. Additionally, comparisons of smoking, systolic and diastolic blood pressure, height, weight, BMI, WHR, total cholesterol, HDL, LDL, triglycerides, and CRP levels between the groups revealed no significant differences. However, a significant relationship was found between age and adenomyosis, with the mean age of the adenomyosis group being higher than that of the other groups (p < 0.05). Conclusion: No significant relationship was found between adenomyosis and known chronic diseases, smoking (pack-years), systolic and diastolic blood pressure, BMI, WHR, total cholesterol, HDL, LDL, triglycerides, or CRP levels. However, the frequency of adenomyosis increases with age.