Synthesis of functionalized thiazoloindole-3-thiones and their spirocongeners from 2-acylethynyl-4,5,6,7-tetrahydroindoles and carbon disulfide
Accessible 2-acylethynyl-4,5,6,7-tetrahydroindoles undergo stereoselective single/double [3+2]-cyclization with CS 2 (NaOH/DMSO) to give 5,6,7,8-tetrahydro-1 H ,3 H -thiazolo[3,4- a ]indole-3-thiones or spirocongeners incorporating Z-α,β-ethylenic ketones.
Authors
- Denis N. Tomilin (ORCID: https://orcid.org/0000-0001-8877-5799)
- Б. А. Трофимов (ORCID: https://orcid.org/0000-0002-0430-3215)
- Igor Ushakov (ORCID: https://orcid.org/0000-0002-6988-9261)
- S. V. STEPANOVA
Institutions
- A.E. Favorsky Irkutsk Institute of Chemistry (RU)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj02380g
- Primary Topic
- Synthesis and Reactions of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00