Effect of Denosumab on Sperm Concentration in Men With Severe Oligospermia: A Randomized Controlled Trial
This RCT showed that denosumab did not improve sperm concentration or alter reproductive hormones compared to placebo. Denosumab is not superior to the vitamin D- and calcium-supplemented men in the placebo group.
Authors
- Martin Blomberg Jensen (ORCID: https://orcid.org/0000-0003-3800-4253)
- Bugge Nøhr (ORCID: https://orcid.org/0009-0009-9744-4452)
- Mette C. Bekker
- Rune Holt (ORCID: https://orcid.org/0000-0002-2489-3216)
- Linda Magnusson Melsen
- Signe Marie Wulff
- Sam Kafai Yahyavi (ORCID: https://orcid.org/0000-0002-6658-5094)
- Christian Paredes (ORCID: https://orcid.org/0000-0001-7631-9702)
- Mads Joon Jorsal
Institutions
- Herlev Hospital (DK)
- Copenhagen University Hospital (DK)
- Gentofte Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1210/clinem/dgaf481
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00