Elevated Serum Soluble Tim-3 in Primary Biliary Cholangitis: Lack of Correlation with Cytokines, Chemokines, and Clinical Parameters
Although sTim-3 and Galectin-9 dysregulation lacked direct clinical relevance, MLR, A/G ratio, cirrhosis status, and inflam matory markers (TNF-α, IL-6, CX3CL1) emerged as robust predictors of disease severity (MELD) and prognosis (MRS1994), highlighting their potential for non-invasive risk stratification in PBC. Cite this article as: Xu J, Ma H, Dang F, et al. Elevated serum soluble tim-3 in primary biliary cholangitis: lack of correlation with cytokines, chemokines, and clinical parameters. Turk J Gastroenterol. 2026;37(2):196-207.
Authors
- C. L. Zhang (ORCID: https://orcid.org/0000-0002-6112-0175)
- Xiàn Yáng (ORCID: https://orcid.org/0000-0002-5019-374X)
- Weimin Bao (ORCID: https://orcid.org/0000-0002-1851-1330)
- Qian Wang (ORCID: https://orcid.org/0000-0002-6514-3470)
- Jingyi Zhang (ORCID: https://orcid.org/0000-0003-4083-6630)
- Haitao Ma (ORCID: https://orcid.org/0000-0002-9107-2928)
- Futao Dang
- Hua Lin
- Yingmei Tang (ORCID: https://orcid.org/0009-0000-5690-4349)
- Junyan Xu (ORCID: https://orcid.org/0009-0008-3582-847X)
- Xu Tan
Institutions
- Kunming Medical University (CN)
- First People's Hospital of Yunnan Province (CN)
- Second People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2025-08-25
- DOI
- https://doi.org/10.5152/tjg.2025.24520
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00