Identification of Proteomic Biomarkers and Therapeutic Targets for Vitiligo Using a Two‐Sample Proteome‐Wide Mendelian Randomization Approach
Our integrative MR analysis identified novel protein biomarkers and promising therapeutic targets for vitiligo, particularly HERC4 and NDC80. These findings offer potential opportunities for improved diagnosis and the development of targeted therapies, advancing precision medicine approaches for vitiligo management.
Authors
- Chunshui Yu
- Lingli Deng (ORCID: https://orcid.org/0000-0003-3105-9104)
- Linli Liu (ORCID: https://orcid.org/0000-0002-7563-3895)
- Jin Chen (ORCID: https://orcid.org/0000-0002-4373-1618)
- Xingyu Pan (ORCID: https://orcid.org/0000-0001-9588-5830)
Institutions
- Suizhou Central Hospital (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1111/jocd.70420
- Citations
- 1
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- National Natural Science Foundation of China
- Chongqing Science and Technology Commission