StemBell Therapy Does Not Significantly Affect Atherosclerotic Plaque Characteristics in a Streptozotocin-Induced Diabetes Mellitus Mouse Model
StemBell therapy did not significantly affect atherosclerotic plaque size or intra-plaque inflammation in a streptozotocin-induced DM mouse model. Future research is essential to explore the potential and limitations of StemBell therapy in DM-related atherosclerosis. The higher mortality of StemBell therapy in diabetic mice compared to the previous non-diabetic mice also warrants further investigation.
Authors
- Klazina Kooiman (ORCID: https://orcid.org/0000-0002-0607-4989)
- Paul A.J. Krijnen (ORCID: https://orcid.org/0000-0002-5399-5617)
- Amber Korn (ORCID: https://orcid.org/0000-0002-1507-9263)
- Mitchell D. Fiet (ORCID: https://orcid.org/0000-0001-6669-5368)
- Hans W.M. Niessen (ORCID: https://orcid.org/0000-0001-9404-9822)
- Ingeborg S. E. Waas
- Suat Şimşek (ORCID: https://orcid.org/0000-0002-0725-2468)
Institutions
- Northwest Hospital (US)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- Amsterdam University of Applied Sciences (NL)
- University of Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Biology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.3390/biology14091130
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Foundation for the Study of Diabetes