Scleroatrophic lichen in women

Anogenital itch and clinical manifestations such as erythema, maceration, cracks, white spots on the skin and mucous membrane of the external genitalia in women may reflect suspected scleroatrophic lichen (SAL) SAL is a chronic inflammatory, non-communicable autoimmune skin disease whose clinical manifestations are atrophic foci that are typically reported in the anogenital region. Despite the disease is quite common, its diagnosis and treatment still present a specific challenge for a medical practitioner. The paper discusses clinical presentation, diagnosis and treatment of SAL. The diagnosis should be confirmed by histological examination of specimens taken from the skin lesions. A dermatologist and a gynecologist should be involved in management of SAL . At the same time, very potent topical glucocorticosteroids (e. g., clobetasol propionate) are the first-line drugs. They are combined with topical calcineurin inhibitors, as well as systemic steroid therapy and methotrexate (if indicated). Timely diagnosis and treatment significantly improve quality of life and prevent complications in the patients. The authors present their own clinical clinical case reports in females with SAL KEYWORDS: scleroatrophic lichen, topical glucocorticosteroids, clobetasol propionate, clinical case, anogenital itching. FOR CITATION: Dvoryankova E.V., Kvach I.V. Scleroatrophic lichen in women. Russian Medical Inquiry. 2025;9(6):327–332 (in Russ.). DOI: 10.32364/2587-6821-2025-9-6-5