Combined minimally invasive vagal cranial nerve and trigeminocervical complex peripheral nerve stimulation produces prolonged improvement of severe painful peripheral neuropathy and hyperglycemia in type 2 diabetes
These findings position combined minimally invasive aVNS and TCC peripheral nerve stimulation as a promising immediate therapy for the current DPN and diabesity crisis, as well as a potential non-pharmacologic alternative for the management of type 2 diabetes.
Authors
- Claire-Marie Rangon (ORCID: https://orcid.org/0000-0003-2173-5607)
- Arthur W. Staats
- Éric Azabou (ORCID: https://orcid.org/0000-0002-9747-9972)
- Peter S. Staats (ORCID: https://orcid.org/0000-0002-4079-5165)
- Jason Chen (ORCID: https://orcid.org/0000-0003-3158-9471)
- Brittny Mikhaiel
Institutions
- Inserm (FR)
- George Washington University (US)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Université Paris-Saclay (FR)
- United States Air Force (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- The Folklore Society (GB)
- Virginia Hospital Center (US)
- International Spine, Pain & Performance (US)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-08-26
- DOI
- https://doi.org/10.3389/fnins.2025.1644961
- Citations
- 2
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 1.68