Live-Attenuated Intranasal RSV Vaccine in Infants and Toddlers

The RSVt vaccine demonstrated promising immunogenicity profiles at both LD and HD strengths among infants and toddlers, without identified safety concerns. (Funded by Sanofi; ClinicalTrials.gov number, NCT04491877).

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Publication Details

Journal
NEJM Evidence
Published
2025-08-26
DOI
https://doi.org/10.1056/evidoa2500026
Citations
3
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
4.06
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Live-Attenuated Intranasal RSV Vaccine in Infants and Toddlers

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NEJM Evidence
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Live-Attenuated Intranasal RSV Vaccine in Infants and Toddlers

Olubukola T. Idoko, Sanjay Gurunathan, Sanie Sesay, Sergio L. Vargas, Peter L. Collins, Iris De Bruijn, Sophie Pallardy, Peyman Banooni, Ursula J. Buchholz, Scott Gallichan, Agustin Bueso, Doris Maribel Rivera, Haritha Adhikarla, Mandeep Singh Dhingra, Eric Gerchman, Rapi Nteene, Enrique Rivas, S A Berger, Michael W. Simon, Camille Vercasson, Monica Gasparotto, Henderson Edward, Stephane Janicot
article en
3 citations

Abstract

The RSVt vaccine demonstrated promising immunogenicity profiles at both LD and HD strengths among infants and toddlers, without identified safety concerns. (Funded by Sanofi; ClinicalTrials.gov number, NCT04491877).

NEJM EvidenceVol. 4(9)
University of Kentucky (US), National University of General San Martín (AR), Sanofi (France) (FR), Sanofi (Netherlands) (NL), Sanofi (Canada) (CA), Honeywell (France) (FR), Sanofi (United States) (US), Matrix Institute on Addictions (US), Paradigm Pharmaceuticals (United States) (US), Universidad Metropolitana de Honduras (HN), Sanofi (Argentina) (AR), National Institute of Allergy and Infectious Diseases (US), Honduras Foundation for Agricultural Research (HN), Sanofi (Mexico) (MX), Matrix Research (United States) (US), Beverly Hills Cardiology (US), University of Chile (CL)
Zero hunger
Openalex Percentile: Top 6%
Respiratory viral infections research
4.06
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