Revisiting the Trans-Ancestry Genetic Correlation of Refractive Error
These results support and extend previous work suggesting that genetic susceptibility to refractive error is largely shared across Europeans, Africans, and South Asians. This suggests geographical differences in myopia prevalence are mostly driven by lifestyle factors or rare genetic variants not considered in the current work.
Authors
- Rosie Clark (ORCID: https://orcid.org/0000-0003-1247-4636)
- Cathy Williams (ORCID: https://orcid.org/0000-0002-9133-2021)
- Jeremy A. Guggenheim (ORCID: https://orcid.org/0000-0001-5164-340X)
- Xi He (ORCID: https://orcid.org/0000-0001-8474-4653)
- Louise Terry (ORCID: https://orcid.org/0000-0002-6200-8230)
- Thu Nga Nguyen (ORCID: https://orcid.org/0000-0002-0879-0006)
- The‐Hung Bui
- Hannah Noor
Institutions
- Twitter (United States) (US)
- University of Bristol (GB)
- ORCID (US)
- Cardiff University (GB)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1167/iovs.66.11.60
- Primary Topic
- Ophthalmology and Visual Impairment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- Government of the United Kingdom
- UK Research and Innovation
- National Institute for Health and Care Research
- British Heart Foundation
- Diabetes UK
- European Commission
- Cardiff University
- Northwest Regional Development Agency
- Moorfields Eye Hospital NHS Foundation Trust
- HORIZON EUROPE Framework Programme
- Medical Research Council