Maternal Obesity and Neonatal Death in Preterm US Pacific Islander Neonates Using 2 Analytic Approaches

In this cohort study of US Pacific Islander individuals, according to the FAR approach, prepregnancy obesity class I and II were associated with an increased rate of NND following PTB, yet these associations may be overlooked when analyses use the birth-based approach. This is likely because prepregnancy BMI affects GA at birth, which, in turn, may have its own confounded association with NND, leading to stratification bias and attenuated associations between prepregnancy BMI and NND using the birth-based approach. The FAR approach offers an alternative that may highlight important risk factors for key perinatal outcomes.