Causes of Death in Anti-IgLON5 Disease: A Novel Case Report and Systematic Literature Review
Sudden death in anti-IgLON5 disease is one of the most common causes of death in the literature. A progressive neurodegenerative process in the brain stem causing central hypoventilation is generally assumed as a major causative factor. The case reported here had concomitant cardiac amyloidosis, which may raise the question as to whether unrecognized cardiac causes, which are not routinely screened for in this population, might represent another cause of sudden death, which would have important therapeutic implications.
Authors
- Petra Schwingenschuh (ORCID: https://orcid.org/0000-0002-3294-6824)
- Christian Enzinger (ORCID: https://orcid.org/0000-0001-9764-7617)
- Petra Katschnig‐Winter (ORCID: https://orcid.org/0000-0001-8403-6227)
- Sebastian Franthal (ORCID: https://orcid.org/0000-0001-7147-9037)
- Stephanie T. Hirschbichler (ORCID: https://orcid.org/0000-0002-9554-4275)
- Romana Höftberger (ORCID: https://orcid.org/0000-0002-5769-1100)
- Mariella Kögl
- Jan Hinrich Bräsen (ORCID: https://orcid.org/0000-0002-2863-3067)
- Lukas Gattermeyer‐Kell (ORCID: https://orcid.org/0009-0009-9699-2959)
- Thomas Seifert‐Held (ORCID: https://orcid.org/0000-0001-8121-3662)
- Tina Howischer
Institutions
- Leibniz University Hannover (DE)
- Medical University of Graz (AT)
- Gesundheitszentrum Bitterfeld (DE)
- Universitätsklinikum St. Pölten (AT)
- Karl Landsteiner University of Health Sciences (AT)
- Hannover Re (Germany) (DE)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Brain Sciences
- Published
- 2025-08-26
- DOI
- https://doi.org/10.3390/brainsci15090921
- Citations
- 1
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39