METTL14-mediated m6A methylation promotes macrophage M2 polarization via YTHDF1-Socs1 axis to accelerate skin wound healing
Socs1 regulates the M2 macrophages polarization and accelerates wound healing, which is modulated by METTL14-mediated m<sup>6</sup>A modification of Socs1 mRNA through YTHDF1 recruitment in macrophages.
Authors
- Jixun Zhang (ORCID: https://orcid.org/0000-0002-6809-6227)
- Chao Wang (ORCID: https://orcid.org/0000-0002-4915-2975)
- Xinxin Dong
Institutions
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s40001-025-03056-7
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81