Association of coagulation dysfunction with thrombosis, bleeding, and mortality in patients supported by veno–venous extracorporeal membrane oxygenation for viral pneumonia
Precannulation reduced TG (<500 nM·min), reduced VWF:RCo/VWF:Ag ratio and increased tissue factor pathway inhibitor alpha levels had significant impacts on major bleeding, which was associated with increased mortality.
Authors
- Mihaela Gaspar
- Golzar Mobayen (ORCID: https://orcid.org/0009-0007-3847-5035)
- Magdalena Gierula
- Michael Laffan (ORCID: https://orcid.org/0000-0002-8268-3268)
- Stéphane Ledot (ORCID: https://orcid.org/0000-0001-9261-3186)
- Josefin Ahnström (ORCID: https://orcid.org/0000-0001-5313-6508)
- Deepa J. Arachchillage (ORCID: https://orcid.org/0000-0001-5993-4850)
- Nilanthi Karawitage
- Farah Kamani
- Saravanan Vinayagam
- Alex Rosenberg (ORCID: https://orcid.org/0000-0001-6580-725X)
Institutions
- Imperial College Healthcare NHS Trust (GB)
- Harefield Hospital (GB)
- Royal Brompton Hospital (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1016/j.jtha.2025.08.010
- Citations
- 3
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- Imperial Health Charity
- Rosetrees Trust