Tumor-informed circulating tumor DNA detection for personalized monitoring of treatment response in epithelial ovarian cancer

This study demonstrates the clinical utility of ddPCR for monitoring treatment responses in EOC by targeting patient-specific mutations. Integrating ddPCR with NGS-based mutation identification offers an effective approach for assessing therapeutic outcomes in EOC patients.

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Publication Details

Journal
Practical Laboratory Medicine
Published
2025-08-26
DOI
https://doi.org/10.1016/j.plabm.2025.e00500
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00

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article

Tumor-informed circulating tumor DNA detection for personalized monitoring of treatment response in epithelial ovarian cancer

Shin‐Wha Lee, M. G. Lee, Ok-Ju Kang, Sung Wan Kang et al.
Practical Laboratory Medicine
Cancer Genomics and Diagnostics
article

Tumor-informed circulating tumor DNA detection for personalized monitoring of treatment response in epithelial ovarian cancer

Shin‐Wha Lee, M. G. Lee, Ok-Ju Kang, Sung Wan Kang, Ji Young Lee, Young-Jae Lee, Yong‐Man Kim, Hee Jung Jung
article en

Abstract

This study demonstrates the clinical utility of ddPCR for monitoring treatment responses in EOC by targeting patient-specific mutations. Integrating ddPCR with NGS-based mutation identification offers an effective approach for assessing therapeutic outcomes in EOC patients.

Practical Laboratory MedicineVol. 47
Ulsan College (KR), Asan Medical Center (KR), University of Ulsan (KR), Korea Institute of Radiological and Medical Sciences (KR), Gangneung Asan Hospital (KR)
National Research Foundation of Korea, Asan Institute for Life Sciences, Asan Medical Center, Ministry of Science and ICT, South Korea
Good health and well-being
Openalex Percentile: Top 72%
Cancer Genomics and Diagnostics
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