Additive-controlled chemodivergent multi-component domino reaction between salicylaldehydes and Morita–Baylis–Hillman (MBH) carbonates
An unexpected additive-controlled chemodivergent multi-component domino reaction of salicylaldehydes with MBH carbonates has been skillfully developed. Interestingly, acid additives regulate the reaction to form functionalized cyclohexenes or natural coumarin derivatives. Notably, the coumarins were produced <i>via</i> a novel phosphine-mediated α-umpolung/Wittig olefination/cycloaddition/lactonization/elimination cascade.
Authors
- Yushuang Chen (ORCID: https://orcid.org/0000-0003-4157-8709)
- Nengzhong Wang (ORCID: https://orcid.org/0000-0003-1690-7611)
- Xiaoxuan Li (ORCID: https://orcid.org/0009-0005-5929-8248)
- Hui Qin Yao (ORCID: https://orcid.org/0000-0002-4450-8602)
- Jing Chen (ORCID: https://orcid.org/0000-0001-7358-4949)
- Nianyu Huang (ORCID: https://orcid.org/0000-0003-4483-160X)
- Yifei Cai (ORCID: https://orcid.org/0009-0000-9118-5298)
- Xin Yu (ORCID: https://orcid.org/0000-0002-9839-3900)
- Dan Xu (ORCID: https://orcid.org/0009-0006-1798-1716)
Institutions
- China Three Gorges University (CN)
- Chongqing University of Science and Technology (CN)
- Chongqing University of Technology (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04624f
- Citations
- 1
- Primary Topic
- Synthesis of heterocyclic compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.94