Comparison of Fexuprazan and Esomeprazole for the Control of Nocturnal Gastroesophageal Reflux Symptoms: A Randomized, Crossover Study

: Fexuprazan was more effective than esomeprazole in controlling nocturnal reflux symptom, particularly in patients with severe symptoms. Fexuprazan may offer a therapeutic advantage for patients with severe and persistent nocturnal reflux despite proton pump inhibitor therapy.

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Publication Details

Journal
Journal of Neurogastroenterology and Motility
Published
2025-08-25
DOI
https://doi.org/10.5056/jnm25119
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparison of Fexuprazan and Esomeprazole for the Control of Nocturnal Gastroesophageal Reflux Symptoms: A Randomized, Crossover Study

Dong Jun Oh, Jiyun Jung, Yun Jeong Lim, Dong Hwan Park
Journal of Neurogastroenterology and Motility
Gastroesophageal reflux and treatments
article

Comparison of Fexuprazan and Esomeprazole for the Control of Nocturnal Gastroesophageal Reflux Symptoms: A Randomized, Crossover Study

Dong Jun Oh, Jiyun Jung, Yun Jeong Lim, Dong Hwan Park
article en

Abstract

: Fexuprazan was more effective than esomeprazole in controlling nocturnal reflux symptom, particularly in patients with severe symptoms. Fexuprazan may offer a therapeutic advantage for patients with severe and persistent nocturnal reflux despite proton pump inhibitor therapy.

Journal of Neurogastroenterology and MotilityVol. 32(1)
Dongguk University (KR), Dongguk University Ilsan Hospital (KR)
Dongguk University, Daewoong Pharmaceutical Company
Zero hunger
Openalex Percentile: Top 67%
Gastroesophageal reflux and treatments
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