Effects of Fructose on Features of Steatotic Liver Disease in HepG2 Cells
This study shows that fructose did not significantly impact TG synthesis or DNL gene expression in the HepG2 cell model. Future studies should consider using primary human hepatocytes or more complex in vitro models.
Authors
- Melanie-Jayne Howes (ORCID: https://orcid.org/0009-0005-4654-2512)
- Jessie King (ORCID: https://orcid.org/0000-0002-3468-3394)
- Rhonda J. Rosengren (ORCID: https://orcid.org/0000-0002-9718-0719)
Institutions
- University of Otago (NZ)
Publication Details
- Journal
- Nutrients
- Published
- 2025-08-26
- DOI
- https://doi.org/10.3390/nu17172762
- Primary Topic
- Diet, Metabolism, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Otago