Base-controlled diastereoselective [3+2]-cycloaddition and Michael addition of isatin ketonitrones and chalcones to construct spiropyrrolidine oxoindoles and γ-substituted isatin ketonitrones
The synthesis of novel spiropyrrolidine oxoindole/γ-substituted isatin ketonitrone derivatives was reported, using [3+2]-cycloaddition/Michael addition of isatin ketonitrone 1,3-dipoles with chalcones under base-controlled conditions.
Authors
- Cuifen Lu (ORCID: https://orcid.org/0000-0002-9040-7861)
- Wei‐Chi Wu (ORCID: https://orcid.org/0000-0003-3760-7255)
- Guizhou Yue (ORCID: https://orcid.org/0000-0001-7811-0531)
- Biao Du
- Chunyan Long
- Lan Ma (ORCID: https://orcid.org/0000-0003-3458-1758)
- Chao Yue (ORCID: https://orcid.org/0000-0003-0026-237X)
- Sicheng Li (ORCID: https://orcid.org/0000-0002-5856-1172)
- He Qiao (ORCID: https://orcid.org/0000-0002-5197-2200)
- Silu Cheng
Institutions
- Sichuan Agricultural University (CN)
- Clover Biopharmaceuticals (China) (CN)
- Hubei University (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj02378e
- Primary Topic
- Organic Chemistry Cycloaddition Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00