Histological examination of the pulmonary artery and aorta in an adolescent undergoing the Ross procedure

Notable pre-Ross histological differences include marked disruption of elastin in the PA compared to the aorta. Age-based differences in Ross outcomes suggest that adolescents may experience proportionally more significant autograft dilation over time, so future studies should include prospective collection and histological analysis of specimens across the age spectrum, both pre- and post-Ross, to allow comparison to age-matched controls.

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Publication Details

Journal
Cardiology in the Young
Published
2025-08-26
DOI
https://doi.org/10.1017/s1047951125101595
Primary Topic
Congenital Diaphragmatic Hernia Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Histological examination of the pulmonary artery and aorta in an adolescent undergoing the Ross procedure

Amer Heider, Rhea J. Birusingh, Peter D. Wearden, Hannah McMullen et al.
Cardiology in the Young
Congenital Diaphragmatic Hernia Studies
article

Histological examination of the pulmonary artery and aorta in an adolescent undergoing the Ross procedure

Amer Heider, Rhea J. Birusingh, Peter D. Wearden, Hannah McMullen, Jennifer S. Nelson, Lili Miles, Camilla Rossi
article en

Abstract

Notable pre-Ross histological differences include marked disruption of elastin in the PA compared to the aorta. Age-based differences in Ross outcomes suggest that adolescents may experience proportionally more significant autograft dilation over time, so future studies should include prospective collection and histological analysis of specimens across the age spectrum, both pre- and post-Ross, to allow comparison to age-matched controls.

Cardiology in the YoungVol. 35(8)
University of Central Florida (US), Cornell University (US), University of Michigan (US), Nemours Children's Health System (US), Michigan Medicine (US), Nemours Children's Clinic (US), Weill Cornell Medicine (US), Florida College (US), Stanford University (US)
Openalex Percentile: Top 64%
Congenital Diaphragmatic Hernia Studies
DOIOpen Access PDFOpenAlex
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Histological examination of the pulmonary artery and aorta in an adolescent undergoing the Ross procedure — Amer Heider, Rhea J. Birusingh, et al. · Cardiology in the Young (2025) | TGRS Research Map | TGRS