Ivermectin inhibits replication of porcine deltacoronavirus <i>in vitro</i>
Our results indicated that IVM interfered with PDCoV genome replication by impairing viral RNA synthesis. These findings suggest the potential of IVM for inhibiting PDCoV RNA polymerase and provide an invaluable therapeutic strategy to combat PDCoV infection with IVM, offering a viable alternative in the absence of commercial vaccines.
Authors
- Guehwan Jang (ORCID: https://orcid.org/0000-0003-3108-8087)
- Duri Lee (ORCID: https://orcid.org/0000-0002-4311-2526)
- Changhee Lee (ORCID: https://orcid.org/0000-0002-5930-5461)
- Sungrae Kim (ORCID: https://orcid.org/0009-0009-6177-6551)
Institutions
- Gyeongsang National University (KR)
Publication Details
- Journal
- Journal of Veterinary Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.4142/jvs.25074
- Primary Topic
- Animal Virus Infections Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea