Successful Early Treatment of Anti‐N‐Methyl‐ <scp>d</scp> ‐Aspartate Receptor Encephalitis Associated With Small Cell Lung Cancer in an Elderly Male Patient: A Case Report

This was a rare case of anti-NMDAR encephalitis associated with SCLC in an elderly male patient. Diagnosis in elderly individuals is often challenging because of the atypical presentations and lower tumor association. Nevertheless, timely intervention initiation may lead to favorable outcomes. Clinicians should consider autoimmune encephalitis, including anti-NMDAR encephalitis, when evaluating acute onset neuropsychiatric symptoms in elderly individuals and initiate early immunotherapy alongside tumor screening.

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Publication Details

Journal
Neuropsychopharmacology Reports
Published
2025-08-26
DOI
https://doi.org/10.1002/npr2.70044
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Successful Early Treatment of Anti‐N‐Methyl‐ d ‐Aspartate Receptor Encephalitis Associated With Small Cell Lung Cancer in an Elderly Male Patient: A Case Report

Ryohei Takada, Harue Goto, Takashi Okada, Yoshihide Honda et al.
Neuropsychopharmacology Reports
Autoimmune Neurological Disorders and Treatments
article

Successful Early Treatment of Anti‐N‐Methyl‐ d ‐Aspartate Receptor Encephalitis Associated With Small Cell Lung Cancer in an Elderly Male Patient: A Case Report

Ryohei Takada, Harue Goto, Takashi Okada, Yoshihide Honda, Kohei Kamikawa
article en

Abstract

This was a rare case of anti-NMDAR encephalitis associated with SCLC in an elderly male patient. Diagnosis in elderly individuals is often challenging because of the atypical presentations and lower tumor association. Nevertheless, timely intervention initiation may lead to favorable outcomes. Clinicians should consider autoimmune encephalitis, including anti-NMDAR encephalitis, when evaluating acute onset neuropsychiatric symptoms in elderly individuals and initiate early immunotherapy alongside tumor screening.

Neuropsychopharmacology ReportsVol. 45(3)
National Archives and Records Administration (US), Nara Prefecture General Medical Center (JP), Nara Medical University (JP)
Japan Agency for Medical Research and Development, Japan Society for the Promotion of Science
Openalex Percentile: Top 68%
Autoimmune Neurological Disorders and Treatments
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