Investigating the orthotic effect of a passive gravity-compensated exoskeletal device on upper-limb function in people with multiple sclerosis: a pilot cross-sectional study
Collaboration between therapists and engineers was key in refining the exoskeleton during phase I. Phase II results supported its positive orthotic effect for PwMS, particularly for those with moderate to severe UL impairments and fatigue. However, for individuals with mild deficits, the device may alter movement dynamics, affecting execution quality. Future improvements should focus on reducing bulk for clinical use. Additionally, studies on larger populations are needed to validate these findings.
Authors
- Ilaria Carpinella (ORCID: https://orcid.org/0000-0001-7486-0706)
- Alessandro Torchio (ORCID: https://orcid.org/0000-0001-5933-7562)
- Marco Caimmi (ORCID: https://orcid.org/0000-0001-9756-888X)
- Tito Dinon (ORCID: https://orcid.org/0000-0002-2309-9280)
- Davide Cattaneo (ORCID: https://orcid.org/0000-0001-8960-4625)
- Thomas Bowman (ORCID: https://orcid.org/0000-0002-9268-3915)
- Rachele Di Giovanni (ORCID: https://orcid.org/0000-0003-4723-9302)
- Erica Grange (ORCID: https://orcid.org/0000-0001-5114-9276)
- Claudio Marcello Solaro (ORCID: https://orcid.org/0000-0002-6713-4623)
Institutions
- University of Milan (IT)
- Multiple Sclerosis Foundation (US)
- Ente Ospedaliero Ospedali Galliera (IT)
- Don Carlo Gnocchi Foundation (IT)
- National Research Council (IT)
Publication Details
- Journal
- Journal of NeuroEngineering and Rehabilitation
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s12984-025-01715-8
- Citations
- 1
- Primary Topic
- Cerebral Palsy and Movement Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Fondazione Italiana Sclerosi Multipla
- Ministero della Salute