Understanding the traits underlying vaccine-driven virulence evolution in malaria parasites
Our results emphasize the complexity of virulence, showing that parasite modulation of host responses can influence disease severity. We also highlight the important role for evolution of parasite traits beyond target antigens in response to vaccination.
Authors
- Nicole Mideo (ORCID: https://orcid.org/0000-0002-8719-3620)
- Tsukushi Kamiya (ORCID: https://orcid.org/0000-0002-9020-6699)
- Yoojung Jeong (ORCID: https://orcid.org/0000-0003-3059-5976)
Institutions
- University of Toronto (CA)
- Collège de France (FR)
- Centre Interdisciplinaire de Recherche en Biologie (FR)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-08-26
- DOI
- https://doi.org/10.1186/s12915-025-02366-w
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Sciences and Engineering Research Council of Canada